Hours before Nevada was set to carry out the country’s first lethal injection using the powerful opioid fentanyl, a judge on Wednesday halted the execution because of a challenge from a drug company that objects to the state’s plan to use one of its products as a sedative for the procedure.

Nevada’s plans to use fentanyl as part of its execution of Scott Dozier — a convicted murderer who has said he wants the lethal injection to proceed — made it the latest in a string of states that have turned to unprecedented drug combinations or uncommon execution methods as they try to carry out death sentences amid difficulties obtaining drugs.

While some other states have turned to comparatively unknown chemicals, Nevada’s plan stood out for relying on fentanyl, a synthetic painkiller that has helped fuel the country’s ongoing opioid epidemic. Depending on what happens in Dozier’s case, Nebraska ultimately could wind up carrying out the first fentanyl-assisted execution, something that state is seeking to do this summer.

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